Researchers Find Possible Clues To Tamoxifen Resistance In Breast Cancer

Breast cancer patients who become resistant to tamoxifen may have low levels of a protein called Rho GDI-alpha, according to a study published online March 30 in the Journal of the National Cancer Institute. Women whose tumors have estrogen receptors (ERs) often take tamoxifen after surgery to prevent recurrence of the cancer and keep it from metastasizing to other parts of the body…

Risk Of Dying From Lung Cancer Reduced By Anti-Estrogen Medication

A new study has found that tamoxifen, an anti-estrogen breast cancer medication, may reduce an individual’s risk of death from lung cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study supports the hypothesis that there is a hormonal influence on lung cancer and that estrogen levels play a role in lung cancer patients’ prognosis…

Breast Cancer Risk In Postmenopausal Osteoporotic Women Reduced By Lasofoxifene

Lasofoxifene statistically reduced the overall risk of breast cancer, as well as ER positive invasive breast cancer in postmenopausal women with low bone density, according to a study published online in The Journal of the National Cancer Institute. Lasofoxifene is a SERM, or selective estrogen receptor modulator, that, like tamoxifen, blocks the effects of estrogen in breast tissue…

Long-Term Survival Improved By Switching Early Breast Cancer Patients To Exemestane

New research has found that switching post-menopausal women with early breast cancer to the drug exemestane (Aromasin) after two or three years of tamoxifen rather than keeping them on tamoxifen for five years improves the chance of remaining cancer free and reduces the risk of death for at least the next six years.

Cost Of Noncompliance Revealed By Study Of Adjuvant Endocrine Treatment For Breast Cancer

The largest study in the world of treatments for post menopausal, hormone positive breast cancer has shown that patients who continue to take exemestane or tamoxifen do significantly better than patients who start to take one or other drug (or tamoxifen followed exemestane) but then stop.

Next Page »